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The additive effect of combining the GSK3 inhibitor LiCl and the standard GBM therapeutic temozolomide suggests possible sensitization due to the induction of differentiation by interference with GSK3 activity.
Our finding pointed to a possible sensitization scheme through combined administration of PI3K inhibitor and cisplatin.
To minimize misclassification errors, we excluded cases classified as possible CBD or possible sensitization from both the disease and normal groups during analysis.
The prevalence of CBD and sensitization to beryllium in former workers at this beryllium production facility in eastern Pennsylvania was high: 7.6% with CBD, 6.9% with sensitization, 2.1% with possible CBD, and 4.0% with possible sensitization.
Despite being submitted to repeated DTH reactions the patients in the present series exhibited a slow rate of DTH conversion, a finding against a possible sensitization by the antigen.
We were not able to compare QFT-GIT test results with TST results since we deliberately omitted TST for the larger cohort to avoid possible sensitization of immune responses.
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Most respondents felt behaviour change was possible with sensitization 'If people will be well educated they will follow [the advice]' [FGD mother 35 year old, 2 children, no schooling] or had already occurred due to health workers advice.
A home dust sample was also collected during the third trimester from subjects and analyzed for standard allergens relevant to maternal exposures and possible prenatal sensitization, based on evidence emerging from the Columbia PCS (Miller et al. 2001).
Respondents felt behaviour change is possible with sensitization and education of those who assist in deliveries: 'If people will be well educated they will wrap the baby even before the placenta comes out' [FGD mother 40 year old, 5 children, educated to standard 7].
Moreover, knowledge of the amino acid sequences that direct binding of HR-E6 to its protein partners further contributes to the potential of developing agents that block E6 binding to its cellular targets, resulting in the possible re-sensitization of HPV-infected cells to normal cell-death-inducing stimuli.
We have analyzed the possible mechanisms underlying sensitization in MOH by comparing these mechanisms with those reported for other forms of drug addiction.
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