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The Reviewing Editor agrees with this reviewer and would like the authors to also entertain this possibility when they describe the possible model of action of the inhibitor.
A possible model of action of the RLCs and of Ctf4 would be that passage through a cohesin loop may require momentary unloading, then re-loading, of PCNA.
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Even with physiological and Psychophysics findings, it is not possible to identify an explanatory model of action of alcohol on sensory and behavioral mechanisms of vision.
Here we used a different experimental model, the acupuncture/xerostomia model, to investigate the possible mechanisms of action of acupuncture.
On the basis of these findings, we propose a model depicting the possible mechanism of action of safingol in MDA-MB-231 and HT-29 cells.
According to the results above, the 12 antitumor drugs could be separated well based on their mechanisms of drug action, which may provide a theoretical basis and a novel insight for developing a model to predict a possible mechanism of action of an antitumor compound in the future.
However, interpretability of model predictions to discover a possible mode of action of the query compound is often demanded, e.g., by the OECD guidelines for valid (Q SAR models [3].
The study was designed to assess the possible mechanism of action of MF against mesenteric I/R model.
Another LDA model was carried out to outline some conclusions about the possible modes of action of anthelmintic drugs.
Graphical abstract Possible modes of action of bio-effectors.
The possible mode of action of harpinpss is discussed.
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CEO of Professional Science Editing for Scientists @ prosciediting.com