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In their letter, Krogsgaard et al. speculate about a possible in-effectiveness of non-operative treatment.
Only differences in GI and CV adverse event rates were modelled, with no consideration of the costs arising from any possible differences in effectiveness of the different treatments.
Possible differences in effectiveness between the two therapies will be established through comparison of differences in (SA PASI scores inclusive of 95% CIs.
Secondary aims were to investigate a possible difference in effectiveness between athletes with high and low proprioceptive acuity, and whether predictors of effectiveness could be found.
Further work is needed to elucidate the possible in vitro synergistic effect of combinations of colistin with antibiotics from several classes and their effectiveness in clinical practice.
Other warnings include an increased risk of bleeding, and possible reduction in the effectiveness of the breast cancer drug tamoxifen if both drugs are used together.
One possible difference in the effectiveness of active-learning pedagogies in the hands of different instructors may lie in the extent to which these instructors consider student metacognition when they implement active-learning strategies.
Forecasting models like this can help policymakers anticipate future burdens of chronic diseases and design targeted policies that fight these diseases in the most effective ways possible, both in terms of clinical effectiveness and cost-effectiveness.
50 51 Disease transmission models will play a role in guiding policy makers in determining the effectiveness of possible pandemic countermeasures.
Although it was not possible to compare the cost-effectiveness reported in all four articles, it was possible to compare cost-effectiveness of the pairs with the same denominator.
Such differentiation makes it possible to investigate whether the same behaviour change techniques differ in effectiveness across other modes of delivery, whilst also offering the potential to explain differences in effectiveness across different settings.
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