Sentence examples for possible gene variants from inspiring English sources

However, the existing transcript information for the human genome is still not comprehensive enough to detect all possible gene variants and there lies the great possibility of finding many more CGs and other novel genes [26] using other more sophisticated procedures.

This association has further strengthened the need to evaluate other possible gene variants that may play a role in therapeutic efficacy.

Instead of utilizing a tag SNP approach, as it was not realistic to analyze all possible gene variants and combinations, we selected SNPs that were most likely to be functional (i.e. within exons, non-synonymous and with a minor allele frequency (MAF) of >0.1) and hence more likely to be associated with the development of cachexia.

Efforts, for example, also include genome-wide association studies (GWAS) to identify new candidate genes or whole genome sequencing in small, genetically homogeneous populations to find possible rare gene variants like copy number polymorphisms (CNPs) [19, 20].

It is also possible that gene variants that predispose the father to insulin resistance are inherited by offspring.

Until now, there is no evidence for the possible role of gene variants of the NPY gene in relation to PTSD.

Also, it is possible that some gene variants were not adequately covered, especially those with low frequency or multiallelic polymorphisms, as in ASPN (45) or BMP5 (47, 47).

In particular, the evolution of evidence on breast cancer and the CYP17 MspA1 variant suggests that determination of possible interactions between gene variants postulated to influence risk and nongenetic risk factors would be more efficiently accomplished by pooled analyses, ideally involving all studies of breast cancer, than by attempting to synthesize published information.

On respect of this topic, another paper from de Klerk et al. [ 25] studied the possible association of ABCB1 gene variants with adverse effects of SSRIs which among the antidepressants show a major affinity as substrate for P-glycoprotein.

One possible hypothesis: coffee hounds have gene variants that increase their metabolism of caffeine, "so to maintain levels that give them [the same] fix, they require more" coffee, Cornelis says.

We studied a population of healthy donors rather than patients, due to the possible presence of more confounding gene variants in patients.