In addition, we demonstrated the possible fallacies of this approach without considering the presence of somatic activating mutations in downstream molecules [ 22- 24].
Such regression methods require aggregation of case data and exposures, leading to possible "ecological fallacy" [26].
The reliability of these types of studies is often questioned because of the possible ecologic fallacy.
Finally, another limitation is the possible ecological fallacy that we may be committing to impute the average hours of sunshine from one province to every individual.
This supports a direct link and contradicts a possible "ecological fallacy" as the time frame, which has an abrupt beginning and end, is similar for both the dioxin crisis and the decline in number of Campylobacter infections (21 ).
However, these results need to be confirmed by a more robust information framework, in order to avoid possible ecological fallacy A better assessment of rehabilitation policies requires the construction of composite indicators and the collection of ad hoc longitudinal data.
Limitations of this study include possible ecological fallacy and the lack of personal genetic and life style information from the NHRI database, and details of tumor staging are not available in the NHIRD.
Limitations of this study include the low number of studies included in the analyses, the inclusion of only English language publications, and possible ecological fallacy associated with patient level characteristics.
The use of odds ratios for binary outcomes is associated with less heterogeneity in meta-analysis than is the use of risk differences or relative risks, 12 and possible inferential fallacies exist when relative risk is used in indirect comparison.
