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Finally we show that the manipulation of the molecules on Cu(211) offers the possibility to selective modify their internal conformation realizing the principle of a conformational molecular switch.
An alternative possibility to selective advantage is that these InDels are moderately (or lowly) harmful under the environmental conditions where the birds are maintained but have attained fixation through hitchhiking by being linked to some beneficial mutations under strong positive selection [ 69].
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We analyze the possibility to achieve selective nucleation and island homogeneity as a function of the various parameters (flux, temperature, pit period) able to influence the growth process.
However, the availability of high density single nucleotide polymorphism (SNP) genotyping arrays as well as rapidly emerging bioinformatics tools offer a possibility to reveal selective forces on loci dispersed throughout the genome.
A major advantage … is the possibility to determine the selective accumulation in the targeted tissue by molecular imaging studies … using structurally identical diagnostic compounds" [20].
The concept of "magic bullet" was first proposed by Paul Ehrlich at the beginning of the 20th century, when he conceived the possibility to have a selective compound, linked to a toxin, that would be able to discriminate and kill a disease-causing organism.
Selectivity of compounds between homologous or orthologous proteins can be predicted, offering new possibilities to design selective compounds or predict the suitability of animal models for pharmacodynamic studies.
Moreover, the present methodology is easy to implement, reliable, sensitive, requiring low sample and minimized desorption solvent volume, having the possibility to tune the most selective sorbent coating, according to the target compounds involved.
Prodrugs are seen as a possibility to design medicines which are selective for their therapeutic aim, for example a tumorous cell or a microorganism.
Motivated by the results of the regression analysis, we investigated the impact of the explanatory variables for the possibility to identify candidate loci for selective sweeps.
Contrary to the polymerization in water medium, this selective swelling method gives possibility to increase three times loaded polypyrrole amount and maintain the stability of the colloidal system.
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