The possibility of scaffold-free organ design was suggested because the cartilage tissue increases steadily in size with culture time; indeed, the growth of cartilage tissue starting from an arbitrary shape might be predictable by mathematical expression.
Hence the possibility of the scaffold tilting does not change the phase diagrams for the N-BAR-lipid systems discussed in the main text.
In particular, extrusion-based AM systems have been widely used for fabrication of TE scaffolds due to their ability of processing different biomaterials, their possibility of manufacturing scaffolds in a cell-friendly environment, their high reproducibility and flexibility, and their simple process control in comparison with other AM techniques.
The BioMEDβeta system demonstrates the possibility of obtaining scaffolds with well-defined architecture, using both natural and synthetic polymers.
This new combination of methods offers the possibility of manufacturing scaffolds with interconnected pore sizes ranging from 1.6 to 51.5 μm.
The possibility of using this scaffold as a multifunctional material was further evaluated by the incorporation of a model protein, bovine serum albumin (BSA), either directly into the PDLLA foam or in the NPs that were eventually included in the scaffold.
Though the possibility of modeling the scaffold as an enzyme-like species was considered, we could not assume that either the kinase or the response regulator would always be in excess, a requirement of the substrate in a Michaelis Menten reaction.
The present study demonstrated the possibility of utilizing different scaffolds with varying physical properties as scaffolds immobilized with anti-BMP-2 to participate in AMOR.
Hence the possibility of finding novel scaffolds that are structurally unrelated to known kinase actives is greatly increased.
The objective of this study is to evaluate the possibility of producing porous scaffolds from such glasses.
