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First of all, usage of a single case study design excludes the possibility for replication of the findings [ 36].
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The study shows evidence that innovation in supply chains oriented towards sustainability require the creation of induction instruments by the focal company, as well as cooperation among participants, points out the relevance of the induction framework adopted and its possibilities for replication.
Again, it is not beyond the bounds of possibility that selection for replication speed favours wild type, but at the moment there is precious little evidence supporting that, and much against.
Multiple replication origins have been in silico and experimentally investigated in Haloarcula hispanica, which raise the possibility for comparisons of multiple replication origins in Haloarcula species.
The continuous rounds of cellular proliferation and apoptosis during the menstrual cycle and any pregnancies create more possibilities for mutation during replication than most other tissues and organs, where cellular turnover is less frequent.
Even though there is possibility of false positive findings, these SNPs could have been selected for replication if robust methods were used.
Another possibility for inheritance of histone modifications through replication is that the parental histones carrying the histone-modifications may be reassembled back onto the same DNA sequences on the newly-replicated DNA molecules that they occupied on the parental DNA.
The proposed mechanistic scenario provides a physical driving force for replication and transcription, the perpetual diurnal cycle, offering the possibility for cycles of extensions and mutations and a general trend towards an increase in complexity.
Apart from the possibility that CFS form secondary structures that may impair replication fork progression, novel findings strongly support a role for replication origin density in determining the fragility of CFS.
"We were looking for replication," she said.
He added that his study was "crying out for replication".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com