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Due to the complex handling and administration of the IMP this first trial will be performed in a single center under coordination of an investigator who possesses profound knowledge of all aspects concerning the IMP.
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"Possessing a profound knowledge of architectural history and theory, and embracing the avant-garde, he never merely replicated the status quo," it said.
His profound knowledge struck them with admiration.
His incredibly detailed and profound knowledge was legendary.
Data often give us profound knowledge, if used carefully.
Controlling the quality of thermal spraying requires a profound knowledge of the phenomena involved.
Big words like 'Salafist totalitarianism' and 'Islamo-fascism' certainly help project the illusion of profound knowledge.
The second strand aims to instil a profound knowledge of – and pride in – the Malian heritage.
At least trainspotters had a profound knowledge of, and love for, trains.
She had a profound knowledge of Italian food, and she was utterly passionate about it.
"He is known to have profound knowledge of British and American literature.
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