Sentence examples for positively enriched from inspiring English sources

CIN-positive tumors, which are positively enriched for sets of genes related to mitotic checkpoint, anaphase- promoting complex, DNA damage response, are also enriched for networks of genes built computationally around key repair proteins (MSigDB modules from Pujana et al. [ 45]).

We applied a cut-off for normalized gene set ranks of 0.1 for negatively enriched gene sets and of 0.9 for positively enriched gene sets.

Interestingly, bio-functional categories related to heart disease conditions, such as 'Cell death of CMs', 'Dilation of heart ventricle' and 'Ventricular tahcycardia', were positively enriched, whereas functions related to 'Muscle development and contractility' were negatively enriched in DMD iPSC-CMs when compared with control iPSC-CMs (Fig. 3C).

It can also be noted that RB lay among the most positively enriched E2F1 targets (Table 1).

Equally, genes that were highly over-expressed in murine L-GMP were also positively enriched in human t(8 21) AML patients (Fig 8B; Supporting Information Table S5).

The labeled and positively enriched cells were eluted from magnetic columns by the removal of the columns from the magnetic device.

2*106 of positively or negatively enriched neutrophils were resuspended in 150 µl CM supplemented with either PBS [10 µl/ml], PMA [10 ng/ml], fMLP [0.1 mM] or LPS [2.5 ng/ml] and transferred to microscopic "Press-To-Seal™" silicon chambers (2 cm ×0.5 mm; Invitrogen).

Experiments with highly enriched populations of positively selected CD8+ T-cells from B6-pko, B6-gld, or B6-cdd donors demonstrated that although each of these T-cell populations could promote the initial presence of donor CFU-GM early post-BMT, B6-pko and B6-cdd CD8+ T-cell populations were not able to support long-term peripheral chimerism.

These data show that both total BM cells and the enriched HSC population positively regulated tumor growth.

Of the 5899 sex-biased genes, 3387 were positively biased in males ("male-enriched"), and 2512 were positively biased in females ("female-enriched") (Table 2), consistent with the overall direction of sex-biased gene expression documented in other taxa [ 11- 14].

To further explore the similarity in gene regulation by Wy14643 between PCLS and primary hepatocytes, we took the enriched genes within the positively or negatively enriched gene sets "IRE1α activated chaperones", "metabolism of xenobiotics by cytochrome P450", and "Interferon alpha beta signaling" (Fig.  3), and compared gene expression changes between PCLS and primary hepatocytes.