Sentence examples for positively coupled from inspiring English sources

The 5-HT6R is a G protein-coupled receptor (GPCR) positively coupled to adenylyl cyclase, which exhibits high constitutive activity (Kohen et al., 2001).

This receptor, belonging to the G-protein-coupled receptor (GPCR) superfamily, is positively coupled to adenylate cyclase through the stimulatory Gαs proteins, and its activation results in an increase in cyclic adenosine monophosphate (cAMP).

This result may not be unexpected, however, given that rapamycin induced transcriptomic and translational state changes are positively coupled in yeast [21].

The β2-adrenergic receptor is positively coupled to cAMP generation via the stimulatory G-protein Gαs [4] and Chen et al. proposed that the decrease of migration is mediated by inhibition of MAP kinase signalling.

Apart from GABAB receptors [33], the other main receptor type that is known to be positively coupled to GIRK channels in TC neurons is the adenosine A1 receptor [34].

The reverse PPI, testing whether SMC and rIFC activation during successful stopping was positively coupled with the striatum, was not significant, in line with PPI findings from Duann et al. [43].

Furthermore, the anti-obesity effect and hypolipidemia effects of APS were probably due partly to decreasing the leptin resistance of mice, which would positively couple with the normalization of plasma insulin levels.

It positively couples to adenylyl cyclase and it signals through cAMP (Strohmeier et al., 1995).

Importantly, β-adrenoceptor and 5HT-1 receptor subtypes are positively and negatively coupled to cAMP-mediated signaling, respectively.

More recent evidence suggests that the ability of dopamine to induce seizures depends on activation of D1Rs coupled positively to cAMP signaling.

DP1 is coupled positively to adenylyl cyclase though Gs [ 14] and this results in strong inhibitory effects on platelet aggregation, bronchodilation and vasodilation in humans [ 42, 43].