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Most of the positive signalling receptors from these receptor families associate via a characteristic positively charged amino acid in their transmembrane domain with the ITAM-containing adaptor DAP12 [ 49, 50].
It reduces inhibitory signalling and increases positive signalling".
The positive signalling pathway of netrins that normally activates apoptosis, seems to be inactivated in tumours.
Intracellular kinases mediate positive signalling from surface receptors by phosphorylating critical target proteins whereas phosphatases inhibit this process.
Lack of one of these four components presumably causes the system mediating the respective positive signalling output to shut down.
Out of the blood cultures showing GPC in clusters (n = 119), 45 of the cultures could be discriminated as S. aureus within 6 hours of positive signalling.
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Foreign Protestants initially received positive signals.
They thought they were getting positive signals.
"This is a very positive signal".
Western diplomats cite "positive signals" in recent days.
Third, implementation remains a huge challenge despite some positive signals.
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