Sentence examples for positive replications from inspiring English sources

Publication bias may be present for candidate genes and could have influenced the selection of genes exceeding the threshold of 3 positive replications.

Now a few studies have obtained positive replications, including chromosomal locus and susceptibility genes [ 4, 5].

DYX1C1 has received the largest number of positive replications of all dyslexia susceptibility candidate genes together with different negative reports.

The positive replications have been reported with different SNPs or with opposite alleles of the same SNPs lacking to provide unanimous consensus on the role of this gene.

The real problem is that most of these studies analyzed familial and sporadic patients together, and principally, that no positive replications of previously described candidate genes have been reported.

In contrast, most of the positive replications have been in keeping with the original study by Caspi and colleagues in measuring life events in the five years prior to the outcome.

While PPV increases with the increasing number of positive replication studies, each non-replicated study may dramatically decrease the PPV value.

Hence, we suspect that GCN5 is a major positive replication factor independently of its activity on centromeres.

The importance of replication studies as part of the process of studying genome-wide association is well known and criteria for establishing positive replication have been suggested [26].

Our data indicate that DPB1*03 01 may be the causative HLA allele underpinning this association, however positive replication studies followed by fine mapping will be required to confirm and resolve this association in other populations.

It cannot be excluded that the low viral RNA level detected after transfection with V1 RNA could be a remnant of the RNA used in the transfection (104 viral RNA molecules/cell), and it confirms the positive replication of the other mutants.