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As reported in the Methods section, a "positive" designation required easily-detectable immunoreactivity with three out of five antibodies.
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Why the Seed Plus designation?
It will be a matter of (1) recognizing the potential causes of mtDNA mixtures aside from heteroplasmy and their potential for impact on the data, and (2) developing and applying criteria that address these causes and reduce the false positive heteroplasmy designation rate to the acceptable level.
This was determined, he said, by a computer program that sorted geo-tagged posts into negative or positive sentiment designations, based upon their language and emoticons.
It should be noted that STAT6 was frequently and highly expressed in vascular endothelial cells surrounding blood vessels seen in the specimens; however a designation of positive or negative was used to refer exclusively to STAT6 expression in tumor cells.
For both biomarkers, we used an H-score ≥1 as a cut-off for designation of positive or negative status in accordance with the American Society of Clinical Oncology/College of American Pathologists guidelines for ER and PgR positivity [ 20].
Cultures were checked for the presence of B. burgdorferi by dark-field microscopy for up to 8 weeks after which a final designation of positive or negative was assigned.
A cross-sectional analysis of the valuation effects with respect to, for example, government ownership of banks supports the view that the positive reaction to these designations can be attributed to a Too-Big-to-Fail (TBTF) perception by investors.
Therefore, both "false" positive and "true" negative designations may actually be assigned incorrectly to true phosphorylation sites that have yet to be discovered.
Both studies used manual scoring of immunoblots, and designations of positive specificities at particular MWs may not be consistent between studies (i.e., what our observers agreed was specificity at 26 and 38 kDa may have been, for Marzouki and others 12 observers, specificity at 28 and 36 kDa).
Federal HPSA designations may have made a positive impact on the identification of chronic disease among the most vulnerable HPSA residents, but the management of these chronic conditions has not been optimized to the same extent.
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