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ERBB2 has been also shown to have a positive bidirectional relationship with FASN, in this way influencing de novo fatty acid synthesis [ 23].
Within the overall patients, a positive bidirectional correlation was observed between sCD40L and MIF, and a negative correlation was observed between each of these and IL-6.
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International research has found strong bidirectional positive linkages between poverty and ill health [ 10, 11] and positive correlations between child maltreatment, poverty and caregiver ill health [ 12, 13].
Epidemiological studies strongly suggest a bidirectional positive relationship between mood and cardiovascular disorders (CVD).
Most theories predict a bidirectional positive association between approach-biases and craving [ 6– 8].
On the other hand, increased α-synuclein protein burden may impair autophagy, generating thus a bidirectional positive feedback loop.
Immunoassays involving sample incubation followed by a wash step prior to introduction of labeled analyte are potentially subject to both positive and negative interference (bidirectional interference) by a competing ligand.
Importantly, the false positive rate of the bidirectional promoter definition only increased to a total of 7.5% when changing from 1 kb to 2 kb distance cutoff.
Additionally, due to the introduction of GO annotations and the application of the statistical analysis, this cross-species method was able to provide bidirectional (both positive and negative) relationship between drugs and disease, and more clues about potential biological mechanisms.
Finally, possible relationships for both seagrass density – total nitrogen and seagrass density – sediment grain size could even be bidirectional, causing direct positive feedbacks.
Bidirectional sequencing of positive PCR products were commercially conducted by Shanghai Sangon Biotechnology Co. (Shanghai, China).
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