Sentence examples for positioning of substrates from inspiring English sources

We recently determined the structure of the Bacillus megaterium tyrosinase revealing a residue, V218, which we proposed to take part in positioning of substrates within the active site.

Depending on the size and position of the substituent groups on the aromatic ring, the o-xylene dioxygenase from Rhodococcus sp. strain DK17 possesses the unique ability to perform distinct regioselective hydroxylations via differential positioning of substrates within the active site.

It can be rationalized that mutation at position 336 also influences the positioning of substrate.

Energy minimization routines were used to aid the positioning of substrate within the active site of 11βHSD1.

We conclude that proper positioning of substrate is crucial for the hydroxylation of CTAD as well as for stimulation of O2 activation.

We again emphasize that precise positioning of substrate atoms in the active site is NOT required if the substrate disulfide bond is replaced with a selenosulfide bond, as in the case of peptide III.

In O-acetylserine sulfhydrylase, the interaction of the substrate carboxylate with a substrate-binding loop, highly conserved from bacteria to plants, triggers the closure of the active site to favor catalysis through proper positioning of substrate-binding groups and exclusion of water molecules [ 47– 47].

Table 1 Various crystalline orientations for the samples exposed to the different number of focus shots at 0° angular and at 8 cm axial positions Number of focus shots Angular position of substrates Crystalline planes Mg3N2 (440) Mg3N2 (321) Mg3N2 (332) Mg3N2 (721) 15 0 ✓   ✓   25 0 ✓ ✓ ✓ ✓ 35 0 ✓ ✓ ✓ ✓.

The trajectories of the substrates are therefore rather complex and the multilayer structure depends on the number of rotational axes, the initial position of substrates and the geometrical parameters of the deposition system.

Meanwhile, owing to the low precursor concentration and low molecular kinetic energy, the single domains on substrate B (~ 10 μm) grow much smaller than those on substrate A, as is shown in Fig. 7b, c. Fig. 7 a The schematic experimental setup with the position of substrates A and B. b, c The SEM images of synthesized WS2 films on substrates A and B, respectively.

We synthesized 54 additional peptides with substitutions at this position of substrates S5− S7 with each amino acid (excluding cysteine) and found that the amino acid identity at this position had a less significant impact on activity (data not shown).