Exact(4)
The positive charge is positioned in a loop to extend toward the neighboring Ig-like domain.
So far, all members of the LβH family that have been crystallized share a catalytic histidine positioned in a loop protruding out of the LβH domain.
In Colombini's model, the analogous residue from fungal and human VDAC is positioned in a loop outside the transmembrane region and outside the pore.
It is noteworthy that the S344 is positioned in a loop between two predicted helices in the FBXO28 C-terminus, potentially influencing FBXO28 dimerization and/or SCF activity through a conformational change triggered by CDK-dependent phosphorylation.
Similar(56)
This is supported by the fact that genes which are not separated by a cohesin/CTCF site (i.e., positioned in a common loop) are more correlated in their transcriptional response to cohesin loss than genes separated by one or more sites.
In this study, we have shown using the nanopore method that when the T=T was introduced into a double-chain reversal loop of the hybrid fold the equilibrium between the hybrids changed to favor the conformation with T=T positioned in an edgewise loop.
In addition, p53 (PDBid 1TUP) (Cho et al. 1994) is the only structurally characterized protein where the O-GlcNAcylation site is positioned in a fully defined loop, thus allowing us to further compare our results (Schimpl et al. 2012).
We therefore propose that GAP and DHAP form Michaelis complexes to the L6RM, which are destabilized by interactions with the twisted loop, and that these complexes isomerize to the active loop-closed enzyme, with loop 6 positioned in a manner similar to that for wild-type cTIM.
Arg222/197 positioned in the loop between α1 and β25 (residues 221 232 in NeuO) forms a polar contact with Thr113/8 7located in the LβH-domain of the same subunit, thereby stabilizing the orientation of this loop.
In an initial homology model, Pro1875.36 at the N terminus of TM5 was positioned in the loop (EC2), although prolines are known to introduce kinks or terminate helices.
This insertion is positioned in the loop structure next to α-8, which is localized to the middle of the mapped epitope region (Fig. 1A and B).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com