Thus, our findings suggest that ERMD functions to position division sites in proximity to nucleoids to increase the probability of their distribution upon mitochondrial division.
To further investigate the functional significance of these observations, we explored the idea that ERMD serves to position division sites adjacent to actively segregating mitochondrial nucleoids, which is based on the observation that ERMES is spatially linked to actively replicating mitochondrial nucleoids (Hobbs et al., 2001; Meeusen and Nunnari, 2003).
Therefore, positioning divisions apically in pseudostratified neuroepithelia could serve to safeguard epithelial integrity and enable proper proliferation and maturation.
We examined body mass index, calculated using coach-reported height and weight, by player position, division, and success based on win-loss percentage.
We also provide evidence that ERMD positions division sites adjacent to mitochondrial nucleoids to bias their distribution into newly generated tips following division.
We study a number of systems involved in cell division in bacteria, including the Min system that helps position the division apparatus at midcell.
We speculate that the change in intracellular levels of ATP disrupts cell division by interfering with ATP-dependent proteins like MinD and FtsA, which are responsible for positioning the division septum at the cell equator[41], [42].
Strategies to position the division apparatus exhibit a bewildering diversity [ 1], but how these mechanisms evolve remains virtually unknown.
This is the first report that a nucleolar protein is required for positioning the division plane during early embryogenesis in Arabidopsis.
Using cortical cues to control actomyosin tethering may allow S. japonicus to dynamically position the division site by reading out the state of the polarized growth machinery, rather than through tracking the nucleus.
