Sentence examples for position substitution from inspiring English sources

The results are shown in Table 2. Surprisingly, the third-codon position substitution rate is positively correlated to body mass and maximum longevity in passerines birds.

Structure activity relationships (SARs) and docking studies indicated that replacement of urea group of sorafenib by chalcone ketones improved the cytotoxic activity, and the results suggested that halogen [3-Br, 4-F] and methoxy (substituted on C-3,4,5 or C-2,3,4 position) substitution was benefit for the activity.

In first way, the chemical reagents at R groups were filtered by docking of scaffold with single position substitution, that is, only at R1, or R2, or R3, … Rn on COX-2 enzyme using Glide XP docking mode.

The preliminary SAR reveals that a substituent and its stereochemistry at C-3 position, substitution (X) at N-2 arene and a linker (Y) between C-3 position and its attached arene are important for the fused-ring scaffold of pyrrolidino [1,2-c]imidazolidinone to block the active site of NS2B-NS3 protease.

Holding the N2 position substitution constant for each of these lead compounds, we turned our attention toward optimizing the quinazoline core.

The average cytb third codon position substitution rate was 0.027 substitution/site/Myr, and the median was 0.018 substitution/site/Myr.

In both of these six-codon families, the synonymous first position substitutions behave like synonymous third position substitutions.

After removing these 10 TEs, the number of third position substitutions in the remaining set was identical to the average of first and second position substitutions.

First, while the majority of third codon position substitutions are synonymous (having no effect on a translated protein's amino acid sequence) and therefore presumably neutral, a small proportion of third codon position substitutions are nonsynonymous.

Further modifications to the quinazoline core ultimately afforded two probe compounds ML241 and ML240 bearing different N2 position substitutions on distinct quinazoline core scaffolds.

There were frequently single nucleotide differences between sequences in contigs, but these differences were usually restricted to silent third position substitutions.