Sentence examples for position stabilized from inspiring English sources

With Elan's financial position stabilized, Mr. Martin wants to refocus on its drugs pipeline, which includes research with Wyeth into a treatment for Alzheimer's disease, and the development of Antegren, a drug for autoimmune disorders like Crohn's disease and multiple sclerosis that Elan is working on with Biogen.

These data are most consistent with dephospho-threonine at this position stabilizing the closed state.

Nevertheless we cannot exclude that a detergent molecule in this position stabilizes the outward-facing conformation.

Our data suggest that the presence of a threonine at this position stabilizes the inactive state and that any change to this residue is likely to destabilize the inactive state of AP2.

Tyr48 is involved in a H-bonding interaction with a heme propionate, and it is likely that introduction of lysine at this position stabilizes the propionate negative charge and destabilizes the ferric heme state.

In the case of the sulfonamides, possibly the OH group in the ortho position stabilize the developing negative charge on the nitrogen through intramolecular hydrogen bonding, and in this way the ionization increases.

"But we've just got to get positions stabilized and get the people who are going to be in the backup roles prepared and ready to go".

The Ara4N moiety is found in the C1 conformation and its positioning, stabilized by interactions with both the protein and cofactor, is compatible with catalysis.

These findings are in line with our previous study, and reveal that the presence of a chlorine atom in the 3-position stabilizes the ligand receptor complex through the formation of a halogen bond with Thr5.39 residue of 5-HT1A and 5-HT7Rs [8].

This attack is facilitated by a water molecule in the active site and the phenolic oxygen of the PLP (1) molecule.[ 39] The phenolic hydroxy group in the ortho-position stabilizes the Schiff base in both cases through a hydrogen bond.

This enables the acrobot to be swung up from the straight-down position and stabilized at the straight-up position.