Hence, the positioning of the division plane may be at a random position close to the center of mass, which can be interpreted as something in-between our COM and Random positioning mechanisms.
We analyzed ase1Δdis1Δ cells, which showed the largest defects in the positioning of the division plane and were the most sensitive to the MT depolymerizing drug MBC (Figure S4).
More importantly, the mutation impaired cell elongation and the positioning of the division plane of the zygote, which led to early embryo arrest.
The heart of this model is that asymmetric positioning of the division septum is all that is necessary for compartment specific stabilization and activation of SpoIIE.
We also note that several groups have discovered that Ric-8 protein plays a key part in the positioning of the division axis in Drosophila morphogenesis [ 40, 41].
They are required for embryo sac development [ 24] and the correct positioning of the division plane during early embryogenesis [ 28], respectively.
In conclusion, YAO is a nucleolar protein with seven WD40-repeats that plays a role in embryo sac development and is critical for the correct positioning of the division plane of zygote and the apical cell lineage in Arabidopsis.
Positioning of the mitotic spindle at the cell center is critical for symmetric cell division, as it defines the origin of sister chromatid segregation and the position of the cell division plane [ 72].
