Exact(10)
Mutagenicity of NBPs was associated with the position of substitution of the nitro function when nitrogen dioxide (NO2) was substituted at the third position on the benzo[a]pyrene (BP) structure, as in 3,6-dinitrobenzo[a]pyrene but not in 1,6-diNBP.
We show that, depending on the position of substitution site, nitrogen produces different effects.
The electrochromic properties of two EDOT-naphthalene-EDOT style polymers are dependent on the position of substitution.
Therefore, the difference between the most potent and least potent ligands lies in the type of substituent and position of substitution on the pendant phenyl group.
The values (π=2.69 4.44) vary depending on the position of substitution on the carborane cage and the isomeric form (o-, m-, p-carboranes).
Nature and position of substitution in aryl ring at 2nd position of benzofuranone influences hMAO-B inhibitory potency, while their structural bulkiness influences selectivity between hMAO-A and hMAO-B.
Similar(50)
Plugins allow one to view various aspects of the data, such as the chromosomal distribution of potentially antigenic genes or the three-dimensional position of substitutions superimposed on solved protein structures.
Exhaustive matching with no restrictions on the position of substitutions was introduced in the SMILE [ 43] and Weeder [ 44] algorithms, where the exhaustive search for the exponential number of candidate consensuses was implemented with the preliminary indexing of the sequences with a suffix tree [ 50].
We first tested if a single amino acid substitution position (regardless of substitution type) was associated with death by day 100 after adjustment for important patient risk factors.
We then further analyzed the positions of substitutions in the Columbicola spp. symbiont 16S rRNA sequences in accordance with a position-specific variability map computed previously using 3,407 bacterial 16S rRNA sequences [ 16].
Positions of substitutions are described as amino-acid locations inferred from an alignment with reference sequences of Mus musculus acquired from the NCBI RefSeq protein database [Genbank: YP001686700 for CO1, NP904331 for CO2].
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