Sentence examples for position of integration from inspiring English sources

The enrichment is independent from the relative position of integration sites with respect to genes and TSSs, since it is present in intergenic as well as in TSS-proximal and intragenic integrations (grey, yellow and green box plots respectively in Figure 2B).

Transient expression or random integration based cell lines are widely used for protein expression, but these technologies have several significant shortcomings including time-consuming, unpredictable and unreproducible levels of gene expression primarily due to lack of control over the position of integration.

After confocal microscopy, quantitative analysis of the 3D radial nuclear position of integration and control loci was performed with the BAC signals only.

Individual sequence reads are masked to remove non-genomic sequence, aligned to the host genome and assembled into contiguous fragments used to pinpoint the position of integration.

Recombinant BoHV-4 could theoretically combine the efficiency of a viral delivery system with that of an artificial chromosome, thus alleviating the influence on gene expression of the position of integration into the host genome.

T1, T2, T4 and T5 showed varying degrees of partial complementation, possibly due to differences in expression levels due to copy number or position of integration affects, but these were not studied further as the aim was to show that Cre2 had the same function as CreB, rather than a complete analysis of the transformants.

Retroviral integration in human cells was investigated in a HeLa-, a T-lymphocyte and an astrocyte cell line previously generated by infection with HIV (see methods) but with hitherto unknown genomic positions of integration sites.

Mapping results are further discussed in Additional file 1: Notes.The 5′-mapped regions were considered to be the positions of integration sites and reported as (chromosome: position: (strand)) for example, (chr1 121251270:.

The position of these integration points (or stress points) is chosen such that the numerical integration is exactly for linear stress distributions.

The distance was calculated by subtracting the position of the integration from the midpoint of the epigenetic feature.

The position of transgene integration was estimated on chromosome 16 to be near cytogenetic bands B3 to C2.