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The striking similarity of the mapped positions in the gene upstream region (in bold, panel A) and less defined rotational phase of the DNA upstream of -100 bp suggests that the nucleosomes upstream of -70 bp position are directed by the SNR6 sequence.
On a gene locus, multiple nucleosome positions are directed by a gene sequence to provide a pool of possibilities, out of which the preferred ones are selected by the chromatin remodeler and transcription factor of the gene under different states of activity of the gene.
In the available HA crystal structure, residue 374 (corresponding to HA2-subunit position 47) is directed into the cavity where the fusion peptide resides in the mature fusion-ready form of the HA molecule [12], [15].
In this position, the carboxylate is directed above the β2-strand where it forms a hydrogen bond with the amido side chain of Asn 289.
The A. fumigatus remains stationary as the stage is positioned such that the particle is directed adjacent to a RAW cell.
Its nearest replacement today is directed to the position rather than the purpose of the lounging: couch potatoes.
Arylation takes place in ortho position to the amine functionality and is directed by the pyridine N-substituent.
I could understand people's anger, I just did not want to be in a position where it was directed to me where I was doing my job".
Due to Germany's deteriorating position, the flotilla was directed in January to leave Norwegian waters and return to the Baltic.
The modified nucleotides in SOMAmers are designed to maintain canonical base-pairing [24], [27] (in a DNA duplex, adducts at the 5-position of pyrimidines are directed toward the major groove of DNA) and hybridize effectively to unmodified DNA oligonucleotides on the array (this is also required for replication during SELEX).
We therefore first determined, and confirmed, that archaeal nucleosome positioning in vivo was directed by same sequence motifs in M. thermautotrophicus and T. kodakarensis and then focused on T. kodakarensis, as the experimental system, for which genetic procedures and strains with histone genes deleted were available [ 13].
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