P450s catalytic motifs were found as expected in all CYP97A/B/C protein sequences including I-helix involved in oxygen binding (CD6 in CYP97B and CD5 in CYP97A and CYP97C), an ERR triad (CD7 in CYP97A/B/C) responsible for locking the heme pockets into position and assuring stabilization of the conserved core structure, and CD10 associated with the conserved heme-binding cysteine.
I finally stammered out something that sounded vaguely like a threat, which had them holding their hands up in "Whoa!" positions and assuring me that I would be allowed free run of the place.
Another motif called the E-R-R triad is thought to be important for locking the heme pocket into position and to assure stabilization of the conserved core structure.
The second conserved motif EXXR (located at position b in fig. 1) and the third consensus PER (located at position c in fig. 1) form E R R triad that is important for locking the heme pocket into position and to assure stabilization of the core structure (Deng et al. 2007; Kelly et al. 2009).
If she serves the next two terms as the No. 1 Democrat in the House, she will have spent 20 years in that position and practically assured through rule changes that no one else could ever do the same.
His job was to encourage communication and assure consistent positions.
A statement the committee issued said, "He said that his departure from the position was amicable and assured the committee that his decision had nothing to do with any integrity issue at The Journal.
Can we be confident, that after a decade-plus of funding cuts, federal health agencies are in a position to assure our protection and at the same time advance innovative studies that will deliver vaccines and other preventive strategies, as well as effective treatments and cures?
Howard Dean raised at least $15 million in the fourth quarter, bringing his total for the year to more than $40 million and assuring his position as the leading fund-raiser in the Democratic presidential race.
Henry was trusting and not a man of war, but Margaret was more assertive and showed open enmity towards Yorkparticularly after the birth of a male heir that resolved the succession question and assured her position.
