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The highly flexible nature of carbohydrate structures differs in many aspects from other biomolecules, posing significant challenges for studies employing computational simulation.
But the problems at Wachovia, while not as severe as those at many other banks, are likely to get worse, analysts said, posing significant challenges for whoever fills Mr. Thompson's shoes.
Increasing numbers of molecular subgroups require an equally increasing number (and new generation) of highly selective agents targeting inevitably lower incidence molecular segments, posing significant challenges for drug development.
In particular, the inversion of WM/GM signal contrast appears around 6-8 mofths of age, where brain tissues appear isointense and hence exhibit extremely low tissue contrast, posing significant challenges for automated segmentation.
Persisters underlie persistent and latent infections and post-treatment relapse, posing significant challenges for the treatment of many bacterial infections.
The globalization of migration flows has increased multicultural diversity, which also importantly contributes to posing "significant challenges for both policy and research" [ 5].
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High-dimensional problem domains pose significant challenges for anomaly detection.
Autumn olive (Elaeagnus umbellata) poses significant challenges for forest managers.
These sources of uncertainty pose significant challenges for policy design, monitoring, and evaluation.
That could pose significant challenges for banks seeking to raise capital and return bailout money quickly.
This poses significant challenges for the management of estuarine ecosystems and their adjacent seas worldwide.
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