Sentence examples for poses substantial problems from inspiring English sources

Extending the high-income tax cut does little for demand and poses substantial problems of fairness and fiscal prudence".

Much remains to be learnt about the strategies N meningitidis employs to evade aspects of immune killing, including mimicry of host molecules by bacterial structures such as capsule and lipopolysaccharide, which poses substantial problems for vaccine design.

For example, notification of security breach incidents poses substantial problems for U.S. businesses and will continue to do so as the frequency of breaches increases and American companies struggle to comply with a competing patchwork of state laws and regulations at home while facing growing pressure abroad from the EU for greater transparency.

During the last few years, A. baumannii has been increasingly isolated from severely ill patients, and its usual cross-resistance to most available antimicrobial drugs, including carbapenems, poses substantial problems worldwide and especially in the United States (1 ).

In the present study, by autoclaving and reusing the patient's own bone, we obviated the need to procure an allograft which poses substantial problems in a country like Pakistan.

From the perspective of public health, an increase of brain tumor incidence of ≥ 50% poses substantial problems for neurosurgical care, but the individual perspective is less dramatic: in industrial countries, the lifetime brain tumor risk is 4 8 per 1,000.

There are some potential matchups that would pose substantial problems for the Spurs, but Popovich, Ginobili, Parker and Duncan alone give San Antonio ample in-series flexibility.

The students of explanation who recognized that probabilities as properties of infinite classes posed substantial problems were few, and those who realized that Salmon's position confronted difficulties of its own fewer still.

This fear could pose substantial problems for pandemic influenza mitigation because those in urban areas may be strongly encouraged to remain isolated to avoid virus spread in conditions of population density and crowding.

For example, Australian wattles have been introduced into the South African fynbos where they pose substantial conservation problems.

There is a high prevalence of oral disease globally and the consequences of oral disease pose substantial public health problems including pain, impairment of function and, reduced quality of life [ 9].