Sentence examples for poses large difficulties from inspiring English sources

It is well known that AT richness and repeat structure of var genes poses large difficulties in the assembly of short sequence reads.

Nonlinearities, uncertainties and large time delay widely exist in the industrial processes, which pose great difficulty to traditional proportional-integral-derivative (PID) control.

Caenorhabditis elegans genes with a large number of exons, short exons, long introns, a weak translation start signal, weak splice sites or poorly conserved orthologs pose great difficulty for gene prediction programs (Williams,G.W. and Davis,P.A., personal observation).

But the multi-algorithm nature of most applications poses many difficulties to classic HW acceleration, particularly large area utilization and difficulty in supporting new algorithms.

We argue that proving a sharp Kramers' law for neural fields poses substantial difficulties, but that one may transfer techniques from stochastic partial differential equations to establish a large deviation principle (LDP).

Such similarity poses a great difficulty in the classification of PGx and neutral variants.

This is because creating a standardized plant medicine poses major difficulties -- especially in a case like marijuana where there are countless, widely varying strains and large numbers of chemical components about which little is yet known.

The lack of consistency between instruments used to evaluate medicine access and the large variability of approaches poses difficulties to compare the studies and confirms the subject as an area under major conceptual and methodological building [ 20].

This poses obvious difficulties for a reporter.

The popularity of digital music services itself poses some difficulties.

But carding the animated avatars that enter poses obvious difficulties.