Sentence examples for poses great difficulties from inspiring English sources

Requiring a furious technique, it rests at the apex of 20th-century piano music and poses great difficulties even for highly accomplished pianists.

This poses great difficulties for the accurate acquisition of product processing information.

It is an understatement to say that this poses great difficulties for the teacher.

The development of coalbed methane (CBM) in China poses great difficulties because of high investments, low production and high risks.

It is interesting to note, however, that the high conditioning characteristic of F3 poses great difficulties to all adaptive parameter control systems.

It is still out of reach to comprehend in an informative way the multiplicity of processes in the path from DNA to protein, which are known to be dysregulated [ 13], and the underlying intra-tumor variation poses great difficulties [ 14 16].

Time delays are frequently involved in these infectious disease models [21 23, 27] and their presence poses great difficulty in stability analysis, especially in analyzing the global asymptotical stability of the equilibria of these models.

Such similarity poses great difficulty in the classification of PGx variants and polymorphisms.

Additionally, one can argue that child anxiety poses greater difficulties for children's engagement in the outside world than in the family sphere.

Amplification of undesired sequences is a common problem in QPCR, and poses greater difficulties when the amplification conditions cannot be tailored to the primer pair of interest, as for example would be the case for massively parallel QPCR.

The vastness of Texas and its contrasts in terrain originally posed great difficulties for transportation, yet they also greatly stimulated its development.