"poses a unique challenge to" is a correct and usable phrase in written English.
You can use it to describe a difficult situation that someone or something must face. For example, "Finding a way to reduce emissions levels in industrialized countries poses a unique challenge to governments and scientists."
His gripping solo style, both artful and seemingly casual, poses a unique challenge to any inheritor.
Terrorism poses a unique challenge to law enforcement because the guilty parties often do not commit a crime until the actual act.
Modern democratic life poses a unique challenge to intellectuals because it is prosaic, operates through public institutions, relies on specialized knowledge and respects common opinion.
The patellofemoral (PF) joint poses a unique challenge to the cartilage surgeon owing to its physiologically high forces (compression and shear) and multiple degrees of mobility.
They'll use their brains to pick apart the program and everyone and everything associated with it, and this poses a unique challenge to anyone who treats them.
Auditory localization poses a unique challenge to the nervous system.
However, these reusable medical devices pose a unique challenge to infection control.
In order to ensure the correct assembly of the respiratory chain, the products of these genes must be produced in the correct stoichiometry and inserted into the membrane, posing a unique challenge to the mitochondrial translational system.
To conclude, multiple chronic conditions and the use of multiple medications are highly prevalent in patients with fibromyalgia and pose a unique challenge to the management of this condition.
These processes, individually or combined, create a myriad different conditions and situations, each of which may pose a unique challenge to children, create specific needs and demand special attention.
Indeed, large stretches of uninterrupted heterochromatic DNA, as found on the Drosophila sex chromosomes, pose a unique challenge to replication (Leach et al., 2000) (Pryor et al., 1980; Collins et al., 2002).
