Sentence examples for poses a significant hurdle from inspiring English sources
Inherent variability in the New Zealand sea urchin, Evechinus chloroticus gonads quality poses a significant hurdle in the design and implementation of processing and shelf-life trials.
Even if the state was not facing a huge budget shortfall, making the case that it needs another law school poses a significant hurdle: who would hire the graduates?
Although this method can produce high-quality AAV vectors when used with multiple purification protocols, one critical limitation is the difficulty in scaling-up manufacturing, which poses a significant hurdle to the broad clinical utilization of AAV vectors.
Its popularity among researchers in signal processing and data mining is not accidental, though its high computational complexity still poses a significant hurdle to overcome.
This poses a significant hurdle for AO drug development as drug developers will be unable to validate the efficacy of AO targeting human dystrophin exon in animal models, which is generally considered to be essential for regulatory approval of clinic trials.
The complexity of the physiological processes regulated by this pathway poses a significant hurdle utilizing and validating it as a bona fide target for neurodegenerative disease therapies.
Thus, VUS pose a significant hurdle in the use of genetic testing data to improve outcomes.
The incomplete understanding of the precise cellular and molecular events that drive disease activity pose a significant hurdle to the development of targeted therapeutic agents.
The accusations pose a significant hurdle for Andersen as Joseph F. Berardino, its chief executive, tries to salvage the firm's reputation and institute reforms as a result of the Enron debacle.
These immune suppressive cells inhibit T cell [47], [48] and NK cell activity [49], [50] and pose a significant hurdle to successful immune based therapy.
However, potential teratogenicity and inhibitory effects on the reproductive system demonstrated by some angiogenesis inhibitors are posing a significant hurdle to the clinical testing of angiogenesis inhibitors in patients with endometriosis.
