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Acquiring IDH1 mutations comes at a price however, as it will pose the cell with an excessive need for exogenous sources of α-KG for sustained membrane synthesis.
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Thus, the new culture system presented here does not pose the same problems as cells can be maintained singly, which is beneficial for the investigation of signalling pathways and cell responses to growth factors, cytokines, and drugs using single cell-based assays.
These signals, such as Wnt and Notch, are critical for the survival and function of somatic stem cells and pose the challenge of delivering a proposed somatic stem cell directly into its tissue niche.
Turn the key on the cell door and you pose the question: how and when will the captive escape?
European security services keep tabs on the group's political supporters, but experts say they are ineffective when it comes to tracking the sleeper cells that pose the most danger.
The process of shearing the cells off the surface poses the issue of possible cell damage and subsequent reduction in viability.
Thus, IG gives us possible grid cells while SSP poses the lower bound to the cell size.
The results obtained with the human HT1080 cells posed the question of whether they were generally true for vertebrate cells.
This poses the question of how cell wall loosening is restricted to the Rop site.
The recognition that gene expression can be substantially stochastic poses the question of how cells respond to dynamic environments using biochemistry that itself fluctuates.
These results posed the question of how cells convert extracellular concentration into proportional periods of signal transduction.
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