Sentence examples for pose significant constraints from inspiring English sources

Simulations of the SCN model with equiprobable mutations show that this approximation is rather good, since one can get correlation coefficients larger than 0.95 between the simulated optimal HP and the PE of single-domain proteins, which would not be the case if the other components of the contact interaction matrix would pose significant constraints.

Auckland's geography poses significant constraints for evacuation planning.

The disease poses significant constraints through reduced productivity and limitation of international trade in live animals and their products [ 2, 3].

The amount of required divergence depends on the specific method used for the deconvolution, but in general, this poses significant constraints in terms of the demographic scenarios that can be analyzed using these methods.

Extremely poor roads and bad bridges, many made of sticks and logs, pose significant access constraints.

These pose important constraints to the solution of dynamic optimization problems related to distributed biological systems.

In Ti-rich alloys, sluggish reaction kinetics between Ti and Zn powder and phase diagram constraints pose significant problems, thus hindering accurate measurement of heat of formation by direct reaction calorimetry.

While pre-therapeutic imaging with surrogate tracers remains the best and only means of adapting the therapeutic activity to be injected (such as 111In or 68 Ga for RAIT or 99mTc for SIRT), it could pose significant organizational issues depending on local constraints (especially for 111In pre-therapeutic studies) as well as additional costs.

The distinct static and dynamic characteristics of output power compared with conventional generations pose significant challenges on power system adequacy and stability and constraints on the penetration level of wind power in power systems.

The complexity of production planning and control process, stochastic factors, physical constraint, uncertainties, and the shortcomings of the underlying IT infrastructure would pose significant drawbacks to the current detailed production scheduling.

Plant viruses and fungi also pose significant and unknown risks.