Sentence examples for pose great difficulty from inspiring English sources

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There are no diagnostic criteria designated for tuberculous optic neuropathy specifically, and the diagnosis of ocular tuberculosis in general continues to pose great difficulty to ophthalmologists.

Nonlinearities, uncertainties and large time delay widely exist in the industrial processes, which pose great difficulty to traditional proportional-integral-derivative (PID) control.

However, this could pose great difficulty for those with specific diseases or those of a low socio-economic level.

Caenorhabditis elegans genes with a large number of exons, short exons, long introns, a weak translation start signal, weak splice sites or poorly conserved orthologs pose great difficulty for gene prediction programs (Williams,G.W. and Davis,P.A., personal observation).

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Complex backgrounds, uneven illumination, and presence of almost unlimited number of text fonts, sizes, and orientations pose great difficulties even to state-of-the-art text detection methods.

The reformulated expectation constraints are also different from general expectation constraints as discussed in stochastic programming areas, which pose great difficulties for the exact proof of convergence of the algorithms.

Whereas modern electron microscopes can routinely deliver images of inorganic material at atomic resolution, biological specimens pose great difficulties for EM imaging, significantly reducing the attainable resolution.

Time delays are frequently involved in these infectious disease models [21 23, 27] and their presence poses great difficulty in stability analysis, especially in analyzing the global asymptotical stability of the equilibria of these models.

Such similarity poses great difficulty in the classification of PGx variants and polymorphisms.

This confusion posed great difficulty for the principal of this particular school: "So we were left then to split our attention three ways: we had to deal with the students who hadn't heard the media reports and came to school anyway, and we dealt with those in exactly the same way as the whole student body had the media not been alerted before us.

In this study, such ratios were found to be effective in determining which areas, due to their infrastructure design, pose greater difficulties for evacuation.

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