"pose fundamental challenges" is correct and usable in written English.
You could use it in a sentence like this: "The rapid changes in technology pose fundamental challenges for businesses."
Space heating and cooling pose fundamental challenges to the achievement of EU decarbonization targets.
More importantly, insulator surfaces pose fundamental challenges when aiming for on-surface reactions.
Nevertheless, poor photoconversion quantum yields and low bandwidth pose fundamental challenges to fascinating applications of hot-electron optoelectronics.
"The demographic developments analysed in the report will pose fundamental challenges for policymakers across the world in the years ahead," said Christine Lagarde, the IMF's managing director.
However, spatial and temporal intra-tumoral heterogeneity pose fundamental challenges to representative sampling and consequently the feasibility of a personalized medicine approach.
The integration of large amounts of variable renewable energy poses fundamental challenges to the operation and governance of the energy system.
The dynamic nature of mobile ad hoc networks poses fundamental challenges to the design of service composition schemes that can satisfy the end-to-end quality of service requirements and minimize the effect of service disruptions caused by dynamic link and node failures.
At the same time, unequal societies are more likely to pose challenges to rights protections". Its top 10 list of challenges include the business role in rising inequality and the rise of internet-enabled work or the "gig economy". "This trend also poses fundamental challenges to the nature of work.
Utilizing UNISDR EWS as a baseline framework in the case of floods and droughts could potentially reduce the impact and effects of such gradual processes, but the integration of hydrometeorological EWS with end-user decision making and planning processes still poses fundamental challenges (Kelman and Glantz 2014).
This poses fundamental challenges to molecular targeted therapy, portending that one molecule-one targeted therapy is not sufficient to treat cancer.
However, implementing correspondingdissectors for the potpourri of formats that today's networks carry, remains time-consumingand cumbersome, and also poses fundamental security challenges.
