The sending off posed a small challenge to Bayern's pride.
This will pose a formidable challenge for a small country with a relatively weak and uncompetitive agricultural sector.
We three vegetarians posed a small problem.
The assessment of tumor invasion of underlying benign stroma in neoplastic squamous proliferation of the larynx may pose a diagnostic challenge, particularly in small biopsy specimens that are frequently tangentially sectioned.
Considering how key content has been as a route to attracting users to these devices, that will continue to pose a challenge for the smaller players.
While most cases of ALK+ ALCL have the common pattern characterized by anaplastic morphology with hallmark cells, a less common but well-recognized variant with a small cell pattern may pose a diagnostic challenge.
Secondly, predicting the MOA of small molecules that target biological processes that are non-specifically associated with numerous perturbations will pose a bigger challenge than those of small molecules that affect pathways that respond to only very few compounds.
2- 4-Aminophenyl benzothiazoles, which are synthetically accessible, small and lipophilic pose a pharmaceutical challenge, as aqueous i.v. formulations would be desired to minimise the possibility of first pass deactivating metabolism and improve drug bioavailability.
Therefore natural hazards, such as avalanches, pose a considerably smaller mental and practical challenge in places where they occur frequently and are expected to do so, as compared to places where they rarely occur, but are more likely to be extreme (Welzer 2009).
Hence, the requirement of individually sampling and genotyping all dying offspring may pose a challenge in species with smaller and more fragile offspring (e.g., mollusks, crustaceans) than newly hatched silverside larvae (∼5 mm SL, ∼2 mg wet weight; Baumann and Conover 2011b).
If only a small fraction of them come to the UK this could pose a significant challenge.
