Sentence examples for pose a significant issue from inspiring English sources

'As-disposed' LNAPL emplaced with the waste is not expected to pose a significant issue.

Tchobanoglous and others insist these substances exist in such small quantities that they don't pose a significant issue.

Given the distinct clinical settings of these disease variants, this does not pose a significant issue in relation to development of an applied gene expression-based classification tool.

Regulatory issues pose a significant obstacle to the development of transgenics and their commercialization.

In Denmark and other European Union (EU) countries, the rapid growth of these intermittent DERs will pose a significant challenge associated with congestion issues in distribution grids.

Without intervention, these mental health issues pose a significant threat to survivors' longer term psychological adjustment.

These issues pose a significant barrier to children's involvement in decisions about their participation in future paediatric critical care trials.

In 2010 the Environment Agency issued a report concluding that the canal "does not pose a significant barrier to salmon movement or impact on migratory behaviours".

Annotation issues of this kind, especially at the 5' ends of genes, pose a significant challenge for correlating promoter histone modification states with transcriptional states.

Two years ago, the inspector general of what is now called the Centers for Medicare and Medicaid Services issued an informal advisory opinion, asserting that substantial upfront payments "appear to pose a significant risk of fraud and abuse".

The inspector general of the Centers for Medicare and Medicaid Services issued a legal advisory in 2000 stating that payments of that type could pose "a significant risk of fraud and abuse".