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"pose a major problem" is correct and usable in written English.
You can use it when expressing a concept of something significant and difficult that needs to be addressed. For example, "Climate change poses a major problem for the future of our planet."
Exact(37)
The migrants pose a major problem for the Chinese.
His size could pose a major problem for the Hoyas' opponents.
The verdict could pose a major problem for individual European airlines.
Fentanyl analogues — or chemical variations of the drug — pose a major problem to law enforcement.
Hospital-acquired infections (HAI) still pose a major problem in inpatient care.
Some cancers continue to pose a major problem: the death rates from liver and pancreatic cancer are rising, not falling.
Similar(23)
Heating the house poses a major problem.
The availability of top-notch microcomputers poses a major problem for postal chess.
I would be very surprised if asylum seekers posed a major problem.
Resistance to chemotherapy and pathway-targeted therapies poses a major problem in cancer research.
The foundations of these high-rise buildings posed a major problem, given the soft clay soil of central Chicago.
More suggestions(15)
pose a severe problem
pose a large problem
pose a fundamental problem
pose a serious problem
pose a major dilemma
represents a major problem
raises a major problem
cause a major problem
causes a major problem
pose a bigger problem
pose an important problem
pose a significant problem
represented a major problem
posed a serious problem
pose a huge problem
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com