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As explained above, tandem duplications pose a hard problem for automatic alignment algorithms.
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Relations with the Soviet Union posed a difficult problem for Roosevelt.
So are vaccines for such vexing diseases as AIDS, a big killer whose variety and rapid mutations pose hard problems for vaccine makers.
The United States command in Iraq has pressed the Kiowas hard to cover convoys, armed raids and surveillance missions, posing a hard test for machines that have had a history of mechanical problems.
Publicity crimes pose a special problem for the press.
The migrants pose a major problem for the Chinese.
Not only do discarded beer bottles pose an environmental hazard, they also pose a serious problem for these beetles.
However, honeybee losses pose a major problem for agriculture.
It's hard medicine for a hard problem".
Yet it might also pose a problem for the prosecutors.
"But that does pose a problem — for Dan.
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