Sentence examples for pose a formidable problem from inspiring English sources

This may already pose a formidable problem as some bacteria might only express narrow pores or mutations might lead to decreased expression of porins, porin loss, or narrow channels [ 4].

The combination of the divine and the human in Jesus posed a formidable problem for 2nd-century theologians, especially the Gnostics, who adopted a cosmological dualism and held that the material world was the creation of the Devil.

King of Castile and Aragon since 1516 and suzerain also over Habsburg lands in the Netherlands, Naples, and central and eastern Europe not to mention the Spanish possessions in the New World Charles posed a formidable problem for the electors.

Ferguson, of course, will have as much influence on Sunday's game as the former Beatle and, despite Louis van Gaal's problems at Old Trafford, Klopp insists the present United will pose a formidable test at Anfield.

Djokovic will certainly pose a formidable challenge for a player who might not be completely healthy.

Any change would take years, and would pose a "formidable challenge".

Not on a classic golf course that will pose a formidable challenge.

Any such undertaking would pose a formidable challenge for leaders today.

Mussina, Andy Pettitte, Roger Clemens and Orlando Hernández, at their most effective, pose a formidable array of starting pitchers.

Now, Mr. Schundler could pose a formidable threat to the Democratic candidate, Jim McGreevey, another moderate.

Seas pose a formidable challenge to climate scientists.