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The portion of differentiated loci was in line with other studies [ 72], confirming that the use of a conservative FDR threshold (5%) and SNP filtering lowered the noise resulting from the use of a high number of polymorphisms.
The portion of differentiated cells was always very small (approximately 20-25%) and at any specific time point only few cells may have been in the process of dying, which may have hindered detection of a "DNA ladder" on the gel.
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We have previously reported that a significant portion of the differentiated human adipocytes have phosphatidylserine on their surface and contained partially fragmented DNA.
Of the invasive carcinomas, tumours comprising a ≥50% tubular-forming component, which included at least a portion of well-differentiated tubular area, were used in this study.
Histological dedifferentiation may occur within a portion of the well-differentiated liposarcoma, resulting in a more aggressive lesion, which is more prone to metastasise and carries a worse prognosis [1].
Previously, the reduction in tumour burden seen with systemic delivery of 5-Aza was largely mediated through ablation of the pleomorphic cell population (<5% of the residual tumour) with a portion of the well-differentiated tumours remaining (Belinsky et al, 2011).
This implied that well-differentiated portion of this tumour was expanded from moderately differentiated portions with accumulation of LOHs at 3p21.3C and 3p14.2.
Vast majority of human breast cancers are adenocarcinomas, and only a small portion of breast cancers are poorly differentiated carcinomas.
The values of CT perfusion in the solid portions of the moderately differentiated HCC occupied an intermediate position between the highly and low-differentiated forms.
Although all 13 rapidly mutating Y-STRs were already multiplexed, no single assay based on single-copy markers allowing at least a portion of close male relatives to be differentiated from one another is available.
According to this classification, 23 primary lung adenocarcinoma samples included 17 well-differentiated portions, 19 moderately differentiated portions and 20 poorly differentiated portions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com