Exact(1)
The regulation of immune system involves the interaction between populations of pathogen and immune cell.
Similar(59)
Supplying the million-plus pounds of feed required daily by the two plants' combined population of seven million hens inevitably involves a good deal of spillage, which in turn attracts large populations of pathogen-bearing rodents and wild birds.
Since the population size of the normal microbiota is large, multiple and different resistant variants can develop, which increases the risk for spread to populations of pathogens.
Any impact of adaptation in the absence of antibiotics on the subsequent cost of additional resistance mutations therefore potentially modulates costs of resistance in natural populations of pathogens.
However, there is little direct evidence that relates degree of multisite cross-reactivity of host immunity to the rate at which natural populations of pathogens generate escape variants.
Even once there are well-established models, the connections between the populations of pathogens or harmful algae and prediction of human health impacts are not straightforward.
The timing of divergence strongly suggests that M. graminicola originated from populations of pathogens associated with wild grasses that then adapted to wheat during its domestication.
The vast-scale and homogenous availability of nutrients in the agro-ecosystem is also expected to enable the development of very large populations of pathogens, thereby increasing the efficiency of selection and accelerating adaptation (Karasov et al. 2010).
Specifically, an important extension of earlier strain theory is to consider the effects of immune selection in populations of pathogens whose antigen-encoding loci are: (a) multi-copy and recombining (i.e., located on different chromosomes of a haploid genome), and (b) undergoing antigenic variation via sequential, mutually exclusive expression within an infected host.
QSS is very well suited to monitoring allele frequency changes in populations of pathogens such as viruses, and probably fungi or bacteria, in either single host extracts or pooled extracts from numerous hosts, provided that the polymorphism at the locus under surveillance is previously identified.
Using an agent-based computational model of an evolving population of pathogen cells, we test this hypothesis and find support for it.
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