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Recent studies showed that, like normal tissues, GBM is composed of heterogeneous cell populations, concerning morphological and differentiation status [ 10].
Moreover, for the interpretation of our results it should take into account the different genetic background of populations concerning HLA class II genes as well as the variable effect of known or unknown predisposing environmental factors.
Differences in patient populations concerning tumour stages may be of importance for diverging results since it is not clear if or how the molecular pattern in tumours changes with progressive disease.
In this respect, it has to be taken into account that A. rubrocincta represents a sibling species complex with considerable plasticity between populations concerning reproductive mode, size, and feeding, but with no obvious morphological differences [ 22].
There exist numerous differences between the Asian and the Caucasian populations concerning anthropometric parameters such as height and weight, genotypes distribution [ 26], as well as geographical latitude and climate parameters.
We therefore predetermined 3 types of populations concerning RFPN: a low-risk group (P1 blood donors and P2 healthy volunteers), an intermediate-risk group (P3 patients investigated for chronic liver diseases, and three high risk groups: tertiary care reference centre (P4), HIV centre and patients from sub-Saharan origin.
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The donors had, in fact, no way of measuring whether those things actually benefitted the populations concerned.
Hence, international action might be taken under the doctrine of humanitarian intervention to liberate the populations concerned from the grip of that movement.
It provides a means to assess the short- and long-term consequences of different policy choices in the context of realistic levels of uncertainty over the status and dynamics of the populations concerned.
The general framework starts with an invisible change in the environment of the populations concerned.
The difference observed in frequency of subgroups could be due to herd immunity or human density of the populations concerned.
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CEO of Professional Science Editing for Scientists @ prosciediting.com