In the Punjab, until the advent of irrigation, most of the population was restricted to those areas receiving more than 20 inches (500 mm) of precipitation annually, namely the Potwar Plateau and the upper Indus plain.
The study population was restricted to those patients with a hemoglobin level ≥7 g/dl, as guideline recommendations suggest considering a transfusion below this threshold.
First, our study population was restricted to Caucasian individuals, predominantly men.
A limitation of this study is that the study population was restricted to patients with acute otitis media or pneumonia.
These data suggested that the CD184+/CD44+ population was restricted in its differentiation capacity to glial lineages.
Eligibility within the VA population was restricted to age as for the HEIRS population (≥25 y men and ≥50 y for women) and to self-reported white ethnicity.
Also, the study population was restricted to women with available blood samples, but excluded women were equally distributed in the groups we compared.
Furthermore, while the income difference between our cohort and the general population was restricted to men, the decrease in risk was also observed among women.
For the purposes of the study reported here, the study population was restricted to the women who were HIV-1 seropositive at enrolment to the trial.
Similar to healthy adults, most of the phylum-level nasal biodiversity observed in the inpatient population was restricted to the Firmicutes (71% of inpatient sequences) and Actinobacteria (20% of inpatient sequences).
In this Phase III trial, the study population was restricted in order to allow comparison of the two treatments and probably does not reflect the baseline clinical and demographic characteristics of the general population of malaria patients in the region.
