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In this context, a recombinant inbred line mapping population (TAG 24 × ICGV 86031) was used to identify markers associated with quantitative trait loci (QTLs) for yield and yield related traits at two important locations of West Africa under well watered and water stress conditions.
Therefore, this study was conducted to phenotype an existing recombinant inbred line (RIL) population (TAG 24 × ICGV 86031) for yield related traits and examine their relationship with yield under well watered (WW) and water stress (WS) conditions in Niger and Senegal, and then compare to QTLs previously identified in an Indian context.
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At this point, the fingerprints collected by a raft of British schools – the same that initially couldn't be used for population tagging – become part of a new and unprecedented power.
We captured all the members of an isolated population, tagged them, and released them back into the field.
The most associated Filipino MHC SNP, rs9271366, which acts as a surrogate marker for HLA-DRB1*15:02 in this population, tags HLA-DRB1*15:01 in populations of European ancestry (r=0.94 (UK controls); r=0.77 (Spanish controls)) and, as such, shows disease association in European SLE with ORs of approximately 1.4 (table S7 in online supplement).
With the TAGster program [ 26], 49 multi-population tag SNPs were subsequently selected for genotyping in the WCHS.
We used a two-step approach to select a set of multi-population tag single-nucleotide polymorphisms (SNPs) that represent common genetic variations - minor allele frequency of at least 0.05 - in VDR in both AA and EA populations.
For CYP24A1, 15 multi-population tag SNPs were selected by using publicly available CEU (Utah residents with ancestry from Northern and Western Europe) and YRI (Yoruba in Ibadan) genotype data from HapMap.
Based on the pattern of intragenic LD that emerged from the re-sequencing panel, we identified SLC2A4 multi-population tag-SNPs (that may be used as surrogates for untyped SNPs [13]), with a threshold r2>0.64.
Therefore, we used information from smolts of other Fraser River populations tagged as part of the POST project to better estimate p on river lines.
Because we did not know in advance the extent to which the population from Sonora would be accurately modeled in polymorphic site frequency and in LD by the EA and IA resequencing populations, tagging polymorphisms were ascertained independently in the IA and the EA populations.
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