Merler, S. et al. Pandemic Influenza A/H1N1pdm in Italy: Age, Risk and Population Susceptibility.
Animal models, epidemiological data, and small clinical trials have favored a causative role for hyperuricemia in hypertension but more studies are necessary to elucidate putative mechanisms, population susceptibility, and potential for urate-lowering therapies (ULT) to decrease blood pressure (BP).
These estimates, along with information on population susceptibility, provided information about the utility or success of different community mitigation strategies.
This phenomenon could be partially explained by higher population susceptibility to pH1N1 than non-pH1N1 virus to which the population might have acquired partial immunity in previous years via prior natural exposure with antigenically-related strains and annual immunization campaigns of a fraction of the high-risk population, with live attenuated vaccines [10], [11], [12].
There was no further spread, but serosurvey findings showed broad population susceptibility to H7N9 virus.
The analyses were stratified by age and sex to study differential population susceptibility.
A combination of alternative factors may be responsible, including differences in population susceptibility.
Our model uses early incidence as a proxy measure of population susceptibility and/or carriage prevalence.
However, this result could be attributable to regional differences in population susceptibility or air pollution mixtures.
Key to this is having high quality systems of coverage and population susceptibility monitoring.
We applied U.S.-based CRFs globally, despite differences in concentrations, air pollutant mixtures, and exposure and population susceptibility characteristics.
