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The population selection process led to an oversampling of individuals with IGR and diabetes.
Details of the population selection process for this study have been published earlier (Einarsdottir et al, 2007).
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In a genetic algorithm, mutation serves the role of either replacing the genes lost from the population during the selection process or providing the genes that were not present in the initial population, exploring new possibilities of solutions [ 33].
By analysing the variation in these genes in a cohort of hunter-gatherer and agricultural human populations, we infer their more recent evolution and discuss whether population-specific selection processes are responsible for the patterns of variation.
On the other hand, because no data were available on SNP frequencies in any North African population, we used data on the CEU and the YRI populations in our selection process.
The most intuitive way to identify driver genes is to detect signals of positive selection across tumor samples because cancer cell populations undergo a selection process during the progression of the disease.
For example, population selection and adjustment processes may dramatically influence the outcome of studies, giving rise to diametrically opposite conclusions [5].
Due to the very high number of permutations that would have to be investigated in order to find the combination of neurons with the optimal population decoding performance, the selection process had to be approximated.
The total number of monomorphic SNPs was set at 100 for each region in all four HapMap populations included in the selection process.
The main steps of GA approach are (Kuo et al. 2001): Chromosome representation Generation of initial population Evaluation of fitness function Selection process Genetic operations (crossover, mutation) Selection of best chromosomes according to the fitness values Termination criteria.
It is taken as given that there are a variety of ways to model any selection process in population genetics; the question here concerns specific information structured into those models.
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