Similar criticism can be applied to the Nottingham Health Profile NHPP) [ 42] and the Quality of Well-Being Scale (QWS) [ 43, 44], which primarily assess the impact of disease and illness, making their applicability to fairly healthy populations questionable.
The generalisability of such findings to specific populations (e.g., obstetric populations) remains questionable, given that the majority of published studies are among elderly populations.
The study was small and restricted to patients with lung disease; therefore, its pertinence to the general population is questionable.
Future studies of preterm birth and SGA should include variables such as hypertension, anaemia and tuberculosis co-infections, although the feasibility of carrying out such a study on a large rural African population is questionable.
The RAID model has shown success in a city hospital, but the generalizability of its effectiveness in different circumstances (eg, rural areas) and a widely distributed population is questionable.
The use of local cutoff points for adiposity status classification in the Romanian population is questionable for several reasons: the lack of population-specific extensive epidemiological data, and the chance of losing the opportunity for international comparison; in clinical practice, it is recommended to use the WHO reference.
By looking at the results of any one study, it is difficult to obtain firm estimate of the overall prevalence and extrapolation of results of one study to the whole population becomes questionable, particularly in a large and culturally diverse country like India.
Syndromic management is an inexpensive and effective method for the treatment of symptomatic sexually transmitted infections (STIs), but its effectiveness as a method of STI control in at-risk populations is questionable.
Moreover, their inter-cultural validity as well as suitability for largely illiterate populations is questionable, indicating use of language independent assessment tools (66).
Given their differential drinking behaviours and physiology compared with people in younger age groups, the external validity of dose-response data drawn from working age populations is questionable when applied to older age groups.
