Exact(4)
The rate or mortality in this study was 5% indicating greater severity of illness making generalization with our OU population problematic.
With more adequate sample sizes these differences were significant but as noted earlier, the quota sampling method makes generalisability to the wider population problematic.
In summary, there are few surveillance studies of alcohol use and alcohol-related problems among children and preadolescents, a situation that makes estimation of alcohol burden in this population problematic.
This structure, however, makes validation of SNP effects in a less-related population problematic, and thus inferences about the usefulness of alternative methods in other livestock species may be difficult.
Similar(56)
More importantly all of the randomized controlled clinical trials included in their report involved active athletes and college-aged patients, making generalizations to older and diseased populations problematic.
Comparison of the lower values for serum and red cell folate that laboratories obtain with these binding assay kits with the values with the L. casei assay also makes interpretation of folate status and adequacy of populations problematic because L. casei assays form the basis for current guidelines.
The implementation of a pneumococcal vaccine trial in the COPD population is problematic because of the large sample size required for studies examining clinical outcomes and the fact that no adequate in vitro assays have been available to serve as surrogate measures of vaccine protection.
Worker productivity and the working-age population are problematic already, and they will likely get worse.
Nonetheless, the excluded items suggest that the competency test within this type of population is problematic.
For instance, directly combining more than one QTL map from the same RI or congenic population is problematic.
One limitation of the tetramer approach is that for CD4+ T cells, it is necessary to gate out dying cells, which means that investigation of mechanisms of cell death in the tetramer-binding population is problematic.
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