Sentence examples for population of plasma from inspiring English sources

In addition, immunohistochemical studies of bone marrow biopsies showed an increased population of plasma cells with the amyloidogenic overexpression of the subunit kappa.

Although our findings are purely exploratory, this study provides an example of how one can attempt to identify an entire population of plasma proteins that characterize a disease state.

In order to rule out multiple myeloma or plasma cells dyscrasia, a bone marrow biopsy was obtained showing a positive expression of CD 138+ (Fig.  2a), a well known marker for identification and quantification of plasma cells in bone marrow and other tissues, as well as an increased population of plasma cells with over-expression of the light chain kappa subunit (Fig.  2b).

In agreement with this prediction, stochastic simulations indicate that for a population of plasma cells subject to continuous presence of TCDD, the number of plasma cells decreases over time in a seemingly exponential fashion with the rate of reversion increasing with TCDD concentrations.

Plasmablasts generated in germinal centers exit the lymphoid organs into the lymph and then the blood, before migrating to the bone marrow or mucosa-associated lymphoid tissues where they represent a long-lived population of plasma cells in a favorable microenvironment, named plasma cell niche.

Analysis of SILAC ratios of the non-biotinylated cytosolic proteins present in the flow-through provided an internal control and did not reveal similar changes, confirming that the effects of AP2 depletion are largely restricted to the population of plasma membrane proteins.

The conspicuous lack of increase of activated B cells or plasma cells in our survey of SLE samples may be due to dissimilarity between the in vitro stimulated B cells and CD138+ purified plasma cells we used and the populations of plasma cells that produce the autoreactive antibodies that are a hallmark of SLE.

Histologic evaluation revealed atrophic lymphoid follicles with small germinal centers and cellular reticular stroma with increased populations of plasma cells (see Figure 2 and Figure 3).

To assure ourselves of adequate numbers of uniform populations of plasma cells, which are scarce in most tissues, we utilized pellets of cultured plasma cell tumor cells that were sectioned and stained as if they had been collected by LCM.

To confirm this and to ask if different populations of plasma cells (i.e. splenic, short-lived versus bone marrow, long-lived) were differentially affected we carried out ELISPOT assays on spleen and bone marrow cell suspensions from immunized mice.

We then calculated the number of HIV-1 infections averted over one year as the difference between the expected HIV-1 infections in a population of 100,000 seronegative persons exposed to HIV-1 infected partners with the indicated population distribution of plasma HIV-1 RNA.